I have two sets of vocings: 5-notes for keyboards and 4-notes for guitar.
I need various inversions to allow for smooth voce-leading and to allow for change of register when necessary.
(The keyboard voicing don't have to be 5 voices)

Here are my ideas:

Keys:
root, 2, b3, 5
root, b3, 5, root, 9
5, root, 2, b3
b3, 5, root, 9

Guitars:
root, b3, 5, 9
5, 2, b3, root
b3, 5, root, 9

Your option 1 doesn't seem playable on a guitar and option 2 has a minor 2nd at the top which seems undesirable.